Preheat oven to 400°F (200°C). Line a baking sheet with parchment paper.
In a food processor, pulse the cauliflower florets until they resemble rice grains.
Microwave the cauliflower rice for 4-5 minutes until soft. Let it cool slightly, then squeeze out excess moisture using a clean kitchen towel.
In a bowl, combine the cauliflower, Parmesan cheese, mozzarella cheese, egg, dried oregano, garlic powder, and salt. Mix well.
Transfer the mixture to the prepared baking sheet and shape it into a pizza crust, about ¼ inch thick.
Bake for 20-25 minutes until the crust is golden and crispy.
Remove from the oven, add your favorite toppings, and bake for an additional 5-10 minutes.